Mushroom polysaccharide is an effective active ingredient extracted from high-quality shiitake fruiting bodies, and is the main active ingredient of shiitake mushrooms. It has immune-enhancing effect. Although its mechanism does not directly kill tumor cells in the body, it can exert anti-tumor activity by enhancing the immune function of the body. Lentinan has been widely used in medicine and food field. Today, the editor of Bona Bio will introduce the application of membrane separation technology in the extraction of lentinan.
Mushroom polysaccharide is generally extracted by water or dilute alkali solution at different temperatures. The purification of the extract includes precipitation method, column chromatography method, preparation high performance liquid phase method, ultrafiltration method, etc. The ultrafiltration membrane separation equipment for the purification of lentinan is based on the principle of mechanical sieving, with a certain pressure difference on both sides of the membrane as the driving force, and adopts the cross-flow filtration method. The separation of the components realizes the extraction of polysaccharides, the sugar yield is high, the technological process is simple, and the extraction time is short.
Advantages of membrane separation technology for lentinan extraction:
1. Using advanced membrane technology materials, strong selective separation and thorough separation of impurities;
2. Physical concentration at room temperature, suitable for the separation and concentration of heat-sensitive substances, retaining the original components of the product;
3. The cross-flow operation mode can solve the problem of pollution and blockage without adding filter aids;
4. Design on-line regeneration cleaning and sewage device to reduce labor intensity and production cost and improve production efficiency;
5. Select 304 or 316L stainless steel sanitary material, in line with GMP requirements.
Bona Bio is a professional manufacturer of membrane separation equipment, with a group of senior engineers in membrane engineering applications. After years of technical development and engineering practice, we have mastered advanced ultrafiltration, nanofiltration, reverse osmosis and ceramic membrane technologies. Focus on designing and producing small test, pilot test and industrial equipment for customers. If you encounter problems in membrane filtration, please feel free to contact us, we will have professional technicians to answer for you.
Post time: Apr-20-2022